Liver Panel on Orals
Focused liver monitoring for anyone running 17-alpha alkylated oral steroids. These compounds pass through the liver and cause predictable enzyme elevations. Catching problems early prevents serious hepatotoxicity.
When to Test
Week 3-4 of oral use, then every 2 weeks while continuing. Immediately if you develop jaundice, dark urine, or severe fatigue.
Testing Frequency
Every 2-3 weeks while running oral steroids. Retest 4 weeks after discontinuation to confirm recovery.
Markers in This Panel(7)
ALT
Liver FunctionPrimary liver enzyme; most sensitive to oral steroid damage. Expect 2-5x elevation.
Ref: 0 – 40 U/L
AST
Liver FunctionSecond liver enzyme; also elevated by muscle damage, so compare with ALT.
Ref: 0 – 40 U/L
GGT
Liver FunctionMost specific for drug-induced liver injury. If GGT rises alongside ALT, the liver is the source.
Ref: 0 – 60 U/L
ALP
Liver FunctionElevated ALP with other enzymes suggests cholestasis (bile flow obstruction).
Ref: 30 – 110 U/L
Bilirubin
Liver FunctionRising bilirubin indicates the liver is struggling to clear waste products.
Ref: 0 – 20 umol/L
Albumin
Liver FunctionLow albumin suggests impaired liver protein synthesis; a late-stage warning sign.
Ref: 35 – 50 g/L
Total Protein
Liver FunctionLiver synthesises most blood proteins; declining levels indicate dysfunction.
Ref: 60 – 80 g/L
Related Compounds
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