Gamma-Glutamyl Transferase

Liver Function marker

GGT

Gamma-Glutamyl Transferase

Category: Liver Function
Unit: U/L

Enzyme involved in bile duct function. Sensitive marker for liver/bile duct issues and alcohol use.

PED Notes

Can be elevated by oral AAS. More specific to liver than AST/ALT since it's not affected by muscle damage. Good confirmatory test for liver stress vs training-induced elevation. If GGT is elevated alongside ALT/AST, liver stress is confirmed. If GGT is normal but AST/ALT are elevated, the elevation is likely from muscle damage, not liver.

Supplements:

  • NAC -- 600-1200mg/day (empty stomach)
  • TUDCA -- 500-1000mg/day (with meals)

Lifestyle:

  • Consider reducing or dropping oral AAS if GGT is elevated alongside ALT/AST

References:

  • Mokhtari, V., Afsharian, P., Shahhoseini, M., Kalantar, S. M., & Moini, A. (2017). A review on various uses of N-acetyl cysteine. Cell Journal, 19(1), 11-17. DOI: 10.22074/cellj.2016.4872
  • Cabrera, D., Arab, J. P., & Arrese, M. (2019). UDCA, NorUDCA, and TUDCA in liver diseases: A review of their mechanisms of action and clinical applications. Handbook of Experimental Pharmacology, 256, 237-264. DOI: 10.1007/164_2019_241

History Chart

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Frequently Asked Questions

Reference Ranges

Standard Range

0 - 60 U/L

VitalMetrics Range

0 - 80 U/L

Statistics