KLOW (BPC-157 + TB-500 + GHK-Cu + KPV)
Pre-mixed healing and anti-inflammatory blend marketed by research peptide vendors. Standard 80mg vial contains BPC-157 10mg + TB-500 10mg + GHK-Cu 50mg + KPV 10mg. Stacks systemic tissue repair (BPC-157 / TB-500) with copper-driven remodelling (GHK-Cu) and NF-kB inhibition (KPV).
Overview
Pre-mixed healing and anti-inflammatory blend marketed by research peptide vendors. Standard 80mg vial contains BPC-157 10mg + TB-500 10mg + GHK-Cu 50mg + KPV 10mg. Stacks systemic tissue repair (BPC-157 / TB-500) with copper-driven remodelling (GHK-Cu) and NF-kB inhibition (KPV).
May accelerate wound and soft-tissue healing, reduce gut and systemic inflammation (CRP, IL-6, TNF-alpha), and improve skin/connective tissue quality. KPV adds NF-kB pathway inhibition on top of BPC-157's gut and tendon repair. Minimal direct impact on hormones, lipids, or haematology. Generally well tolerated.
Compound Guide
Composition (standard 80mg vial):
- BPC-157 — 10mg (pentadecapeptide, gut/tendon/ligament repair)
- TB-500 — 10mg (thymosin beta-4 fragment, soft-tissue repair, anti-inflammatory)
- GHK-Cu — 50mg (copper tripeptide, collagen synthesis, tissue remodelling)
- KPV — 10mg (Lys-Pro-Val tripeptide, NF-kB inhibitor, gut/skin anti-inflammatory)
Note: Composition varies between vendors — some KLOW blends substitute or omit components (LL-37 is included in some older formulations). Always confirm the formulation with the supplier before dosing.
Dosage:
- Standard: 400-800mcg of the blend, SubQ daily
- Loading phase: 800mcg daily for 4-6 weeks (active flare / acute issue)
- Maintenance: 400mcg 3-5x/week
- Cycle: 6-8 week loading, then break or rotate
Administration:
- SubQ injection with 27-30g insulin syringe
- For gut conditions, some protocols use abdominal SubQ for closer local exposure
- Reconstitute with bacteriostatic water (typically 2-3mL for an 80mg vial)
- Store reconstituted vial refrigerated, use within 30 days
Key Notes:
- Marketed for IBD/IBS, leaky gut, chronic inflammatory skin conditions (eczema, psoriasis), tendon and ligament injuries, and post-surgical recovery
- KPV + BPC-157 hit gut inflammation through complementary mechanisms (NF-kB inhibition + cytoprotection)
- TB-500 + GHK-Cu cover deep soft-tissue repair and connective tissue remodelling
- Stack with Thymosin Alpha-1 if immune modulation is the primary goal
- KPV alone is often sufficient and cheaper for mild gut inflammation; KLOW is the heavy-hitter when multiple inflammatory pathways need targeting
- Convenience over flexibility — fixed ratios mean you cannot adjust individual peptide doses
- See individual peptide entries for full pharmacology and safety profiles
- Bodybuilding relevance: gut health on high-food-volume bulks, recovery from oral AAS gut irritation, skin/joint support during contest prep, injury rehab during training cycles
- Monitor: CRP, ESR (if available), and clinical symptoms; consider stool calprotectin if used for IBD
Usage History
Frequently Asked Questions
Quick Reference
Category
Peptide
Half-Life
Variable — BPC-157 ~4 hours, TB-500 ~2-3 hours, GHK-Cu ~minutes (genomic), KPV short (estimated minutes-hours)
Detection Time
N/A