GHK-Cu

Glycyl-L-histidyl-L-lysine copper complex. Naturally occurring copper peptide. Stimulates collagen synthesis, wound healing, hair growth, and tissue remodelling.

Overview

Peptide

Glycyl-L-histidyl-L-lysine copper complex. Naturally occurring copper peptide. Stimulates collagen synthesis, wound healing, hair growth, and tissue remodelling.

Effects on Markers

No significant impact on standard blood markers. May mildly modulate inflammatory markers (preclinical evidence of reducing IL-6, TNF-alpha). Does not affect hormones, lipids, haematology, or liver enzymes. Primarily acts locally on tissue remodelling.

Compound Guide

Structure: Tripeptide (Gly-His-Lys) naturally complexed with copper(II) ions. Levels decline with age — abundant at age 20, significantly reduced by age 60.

Dosage:

  • Skin/hair/anti-aging: 1-2mg/day SubQ, 5 days/week for 8-12 weeks
  • Tissue remodelling: 2mg SubQ 3x/week
  • Topical (skin/hair): Applied as cream or serum directly to skin/scalp

Administration:

  • SubQ injection, abdomen or target area
  • 27-30g insulin syringe
  • Also available as topical formulations for skin and hair applications

Key Notes:

  • Modulates over 4,000 genes — upregulates collagen, elastin, and decorin synthesis
  • Promotes wound healing, tissue remodelling, and reduction of scar tissue/fibrosis
  • Hair growth benefits: promotes follicle size increase (may help thinning from DHT-derived AAS)
  • Anti-inflammatory and antioxidant properties (increases SOD, reduces free radical damage)
  • Popular alongside AAS cycles to counteract skin/hair degradation from androgens
  • Very well tolerated — one of the safest peptides in common use
  • No significant impact on bloodwork — no monitoring changes needed
  • Reconstitute with bacteriostatic water, store refrigerated and away from light

Usage History

Markers to Monitor

Frequently Asked Questions

Quick Reference

Category

Peptide

Half-Life

Unknown (estimated minutes; effects are genomic/long-lasting)

Detection Time

N/A

Usage Summary