TRT & HRT
Starting, dosing and monitoring testosterone replacement: estradiol, hematocrit, fertility, libido and when to test.
16 articles, newest first
Why Your HRV Is Low on TRT (Normal HRV by Age for Men)
Is an HRV of 25 low on TRT? Normal RMSSD by age for men, why wearables disagree, what testosterone, tren, clen and T3 do, and when low HRV matters.
How Much Hair Oral Minoxidil Regrew in Phase 3 (VDPHL01 Data)
Veradermics' extended-release oral minoxidil added 22 to 30 hairs/cm² over placebo in Phase 3. What it means on TRT, with finasteride, and for your heart rate.
How to Fix Crashed E2 on TRT or Cycle (Symptoms and Labs)
Crashed E2 symptoms, the numbers that actually define low estradiol in men, which lab test to trust, and how long recovery takes after each AI.
TRT Does Not Cause Heart Attacks (But Blasting Is Different)
TRAVERSE cleared replacement-dose testosterone for CV risk. It says nothing about bodybuilder doses. The honest line is on your bloodwork, not your syringe.
T:E2 Ratio Guide: Decision Tree, Dose Scenarios & AI Thresholds
How to read your testosterone to estradiol ratio on TRT or cycle. Dose-specific bands, the AI decision tree, the ratio trap, unit conversion for AU/UK labs.
How to Lower Hematocrit on TRT Without Blood Donation
Tiered protocol for managing high hematocrit on TRT. Strategies for 50-52%, 52-54%, and 54%+ levels: naringin, microdosing, hydration, and when to escalate.
TRT and Mental Health: Anxiety, Depression & the First 90 Days
Week-by-week timeline of mood changes on TRT. Why anxiety spikes at week 3, when depression lifts, the SSRI question, and 7 markers to track.
Low Libido on TRT? A Bloodwork-First Troubleshooting Guide
Testosterone optimized but libido still dead? A bloodwork-first protocol: free T, estradiol, prolactin, thyroid, DHT, plus tadalafil, PT-141, and dopamine.
TRT Alternatives: A Decision Guide for Low Testosterone
Not sure if TRT is right for you? Compare enclomiphene, HCG, lifestyle changes, and supplements with real data to find the best path for your situation.
HCG and Fertility on TRT: How to Preserve Your Options
How HCG preserves fertility on TRT, with dosing protocols by urgency, enclomiphene and gonadorelin alternatives, and the bloodwork panel that actually matters.
How to Time Your Blood Draw on TRT
Draw at trough, the morning of your injection day. Peak timing inflates testosterone by 500+ ng/dL, driving unnecessary dose cuts and AI use.
Does TRT Cause Hair Loss? DHT, Genetics, and What You Can Do
Does testosterone replacement therapy cause hair loss? The science behind DHT, genetic risk, delivery methods, and prevention strategies for men on TRT.
The Iron Paradox on TRT: Why Blood Donation Can Backfire
TRT raises haematocrit while depleting iron stores. Learn why phlebotomy can backfire, how to monitor ferritin and sTfR, and what the 2024 evidence says.
How to Recognize High Estradiol on TRT
Symptoms of high estradiol on TRT, target E2 ranges by test, and when an aromatase inhibitor is actually needed. Avoid crashing E2 permanently.
Starting TRT in Australia: Your Complete Guide
Complete guide to TRT in Australia. Testosterone levels by age, clinic options, injection protocols, fertility risks, and blood test monitoring.
TRT, Haemoglobin & Haematocrit: What Actually Matters
Why your haematocrit rises on TRT, when to worry, and why phlebotomy should be a last resort. Evidence-based guide with PubMed sources.