Fat Loss & Metabolic
GLP-1s, retatrutide and other fat loss drugs: what to test, how much muscle you keep, and what the trials actually found.
10 articles, newest first
When Will Orforglipron Be Available in Australia? (TGA Update)
Orforglipron (Foundayo) is not TGA approved yet; the Wegovy Pill is. Realistic Australian timeline, trial results, muscle loss and the bloodwork to run.
Is Imeglimin Better Than Metformin for Lifters?
Imeglimin (Twymeeg) is pitched as metformin plus MOTS-c plus NAD+. Here is what the trials show, what they don't, and the labs to run.
Does Retatrutide Plus Cagrilintide Beat CagriSema for Weight Loss?
Petersen 2026 showed cagrilintide plus retatrutide beat CagriSema in rats. What the paper measured, what the human data says, and what to watch on bloodwork.
How Semaglutide Extended Lifespan 12% in Old Female Mice
A 2026 Nature study added 12% median lifespan in aged female mice on semaglutide. What athletes on TRT should actually take from it, and what to ignore.
Does Eloralintide Protect Muscle Better Than a GLP-1?
Eloralintide is sold on a muscle-sparing promise. The human trials never measured body composition, and the closest amylin data points the other way.
Is AMG 133 Peptide Real? MariTide Results and Bloodwork
AMG 133 is an antibody conjugate, not a peptide, so nothing sold as one is real. MariTide Phase 2 results and when to draw blood on a monthly drug.
Does 5-Amino-1MQ Actually Burn Fat? (No Human Trials Yet)
5-amino-1MQ is an NNMT inhibitor sold for fat loss and NAD+. Here's the real evidence, honest dosing, and the bloodwork to run on it.
How Much Muscle You Lose Cutting on Retatrutide
TRIUMPH-1 showed 28.3% weight loss. Here's how much was muscle, what DEXA data predicts for athletes, and how to preserve muscle on a retatrutide cut.
Retatrutide Bloodwork: The Triple Agonist Monitoring Guide
What to test on retatrutide. Monitoring protocol for the GLP-1/GIP/glucagon triple agonist: liver, thyroid, pancreas, glucose, and muscle markers.
GLP-1 Bloodwork: What to Test on Semaglutide
Complete GLP-1 bloodwork guide. Which markers to test on semaglutide, tirzepatide, or retatrutide, with monitoring protocols for athletes on TRT.