Clomiphene

Clomid. SERM used for PCT to restore natural testosterone production.

Overview

SERM

Clomid. SERM used for PCT to restore natural testosterone production.

Effects on Markers

Stimulates LH/FSH (HPTA recovery), raises testosterone, can cause mood/vision sides at high doses, raises estradiol

Compound Guide

Mechanism: SERM that blocks estrogen at the hypothalamus and pituitary, stimulating GnRH and subsequently LH/FSH release. Mixed agonist/antagonist at different tissues.

Dosage:

  • PCT: 25-50 mg/day for 4-6 weeks
  • Fertility restoration: 25 mg/day or 50 mg EOD (long-term under medical supervision)
  • Avoid high doses (100mg+) -- side effects increase dramatically

Administration:

  • Oral tablet, with or without food
  • Long half-life allows once-daily dosing

Key Notes:

  • Stronger LH/FSH stimulation than Tamoxifen -- preferred by some for aggressive PCT
  • Higher incidence of side effects than Tamoxifen: mood swings, emotional sensitivity, visual disturbances (floaters, blurry vision)
  • Vision sides are dose-dependent and reversible -- discontinue immediately if they occur
  • Often combined with Tamoxifen in PCT protocols (Clomid 25mg + Nolvadex 20mg/day)
  • Enclomiphene (pure isomer) is preferred when available -- fewer side effects
  • Can be used long-term at low doses (12.5-25mg) as an alternative to TRT for maintaining fertility
  • Begin PCT after all AAS have cleared the system

Which markers to order during a restart, when to draw them, and how to read the recovery pattern: PCT bloodwork: when to test and how to know you have recovered.

Usage History

Pairs With

How Clomiphene behaves when it is run alongside other compounds.

Commonly stacked with

Used to offset

Stacks the risk

Frequently Asked Questions

Quick Reference

Category

SERM

Half-Life

5-7 days

Detection Time

N/A

Usage Summary