Clomiphene
Clomid. SERM used for PCT to restore natural testosterone production.
Overview
Clomid. SERM used for PCT to restore natural testosterone production.
Stimulates LH/FSH (HPTA recovery), raises testosterone, can cause mood/vision sides at high doses, raises estradiol
Compound Guide
Mechanism: SERM that blocks estrogen at the hypothalamus and pituitary, stimulating GnRH and subsequently LH/FSH release. Mixed agonist/antagonist at different tissues.
Dosage:
- PCT: 25-50 mg/day for 4-6 weeks
- Fertility restoration: 25 mg/day or 50 mg EOD (long-term under medical supervision)
- Avoid high doses (100mg+) -- side effects increase dramatically
Administration:
- Oral tablet, with or without food
- Long half-life allows once-daily dosing
Key Notes:
- Stronger LH/FSH stimulation than Tamoxifen -- preferred by some for aggressive PCT
- Higher incidence of side effects than Tamoxifen: mood swings, emotional sensitivity, visual disturbances (floaters, blurry vision)
- Vision sides are dose-dependent and reversible -- discontinue immediately if they occur
- Often combined with Tamoxifen in PCT protocols (Clomid 25mg + Nolvadex 20mg/day)
- Enclomiphene (pure isomer) is preferred when available -- fewer side effects
- Can be used long-term at low doses (12.5-25mg) as an alternative to TRT for maintaining fertility
- Begin PCT after all AAS have cleared the system
Usage History
Markers to Monitor
Marker Interactions
Frequently Asked Questions
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Quick Reference
Category
SERM
Half-Life
5-7 days
Detection Time
N/A