Masteron (Drostanolone)

Ester: Available as Propionate (short) or Enanthate (long). Propionate is more common.

Dosage:

• Enhancement (Prop): 300-500 mg/week, injected EOD
• Enhancement (Enanthate): 300-500 mg/week, injected 2x/week

Injection Protocol:

• Propionate: EOD, 25-27g needle, delts/VG
• Enanthate: 2x/week, 25g needle, glutes/VG

Key Notes:

• DHT derivative -- does not aromatise and has anti-estrogenic effects at the receptor level
• Can mask high E2 symptoms without actually lowering estradiol -- be cautious about relying on it as estrogen control
• What it does and does not do to E2, SHBG, haematocrit and HDL, and how to set your test to Masteron ratio from bloodwork: Does Masteron lower estrogen?
• Primarily cosmetic: hardening, drying, mild strength increase
• Works best at low body fat (<12%) -- effects are less noticeable at higher body fat
• Moderate lipid impact -- less harsh than Winstrol but still suppresses HDL
• Hair loss risk is significant (strong androgen at the scalp)
• Often added to contest prep stacks or cutting cycles alongside Test

Compound rankings for HDL damage and the on-cycle protocol that limits it: How to protect your cholesterol on steroids.