TRT / HRTOngoing1-2x per week

True TRT

Physiological testosterone replacement to maintain healthy male hormone levels

Target: 12-30 nmol/L (total testosterone)

Standard testosterone replacement therapy aiming for mid-to-high natural range levels. Suitable for men with clinically low testosterone or as a long-term base. The goal is symptom relief (energy, libido, mood, body composition) without supraphysiological levels.

Compounds

Testosterone Enanthate100-150 mg/week

Frequency: 1-2x per week

Can substitute with Testosterone Cypionate

Dosage Summary: 100-150 mg Testosterone per week

Safety / Ancillaries

Anastrozole0.25-0.5 mg as needed

Only if high E2 symptoms present (gyno, excessive water retention, mood issues)

Supplements

Omega-3

2-4 g/day

Magnesium

400 mg/day

Vitamin D3

4000-5000 IU/day

Zinc

25-50 mg/day

Blood Marker Monitoring

MarkerFrequency
Total TestosteroneEvery 3-6 months
EstradiolEvery 3-6 months
Haematocrit / HaemoglobinEvery 6 months
Liver Function (ALT, AST)Every 6 months
Lipid PanelEvery 6-12 months
PSAAnnually (if >40)

Key Notes

  • Start at the lower end (100 mg) and titrate based on bloodwork at 6-8 weeks
  • Split dose into 2 injections per week for more stable levels and fewer side effects
  • Do not start an AI pre-emptively -- only if E2 symptoms arise
  • Donate blood if haematocrit exceeds 54%
  • Consider HCG 250 IU 2-3x/week if fertility preservation is needed

Frequently Asked Questions

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