Folate

Other marker

Folate

Category: Other
Unit: nmol/L

B vitamin essential for DNA synthesis and red blood cell production.

PED Notes

Important for red blood cell production, DNA synthesis, and homocysteine metabolism. Adequate levels support recovery. Critical alongside B12 and B6 for keeping homocysteine levels in check (elevated homocysteine is an independent cardiovascular risk factor).

Supplements:

  • Methylfolate (5-MTHF) -- 800mcg/day (active form, bypasses MTHFR gene variants)

Note: Usually sufficient with a balanced diet but worth supplementing if homocysteine is elevated

References:

  • Bailey, L. B., & Gregory, J. F., III. (1999). Folate metabolism and requirements. Journal of Nutrition, 129(4), 779-782. DOI: 10.1093/jn/129.4.779
  • Huang, T., Chen, Y., Yang, B., et al. (2012). Meta-analysis of B vitamin supplementation on plasma homocysteine, cardiovascular and all-cause mortality. Clinical Nutrition, 31(4), 448-454. DOI: 10.1016/j.clnu.2011.01.003

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Reference Ranges

Standard Range

7 - 45 nmol/L

VitalMetrics Range

15 - 45 nmol/L

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