Large VLDL Particles
Lipids marker
Large VLDL-P
Large VLDL Particles
Concentration of large VLDL particles. Elevated levels indicate triglyceride-rich lipoprotein overproduction and are strongly linked to insulin resistance.
PED Notes
GH use increases hepatic VLDL production, elevating large VLDL-P. Insulin use (common in advanced bodybuilding) and insulin resistance from GH compound this. High-calorie bulking diets (especially high-carb) drive VLDL production. Oral AAS affect hepatic lipid metabolism, contributing to VLDL elevation. Elevated large VLDL-P correlates strongly with the LP-IR score.
When high
Supplements:
- Omega-3 (EPA/DHA) -- 2-4g/day (most effective for reducing VLDL)
- Berberine -- 500mg 2-3x/day before meals
- Niacin -- 500-1000mg extended-release
Lifestyle:
- Reduce refined carbohydrates and sugar
- If on GH, consider dose reduction if persistently elevated
- Regular fasted cardio may help reduce VLDL production
- Fasted blood draw essential (12h minimum) for accurate reading
Educational information, not medical advice. Nothing here is a prescription or a treatment plan, and it does not account for your history, medications or conditions. Use it to ask better questions: bring it to your doctor and decide together. Full disclaimer.
History Chart
Reading History
Frequently Asked Questions
Reference Ranges
Standard Range
VitalMetrics Range