Anticardiolipin Antibody IgM
Inflammation marker
Cardiolipin IgM
Anticardiolipin Antibody IgM
The IgM class of anticardiolipin antibody, part of the antiphospholipid antibody panel used in the diagnosis of antiphospholipid syndrome. IgM positivity is less specific than IgG and more often transient.
PED Notes
Anticardiolipin IgM is not affected by AAS, GH, or peptides. Like the IgG class it flags antiphospholipid syndrome, a clotting disorder that compounds the thrombotic risk androgens create through erythrocytosis and prothrombotic haemostatic changes. IgM is more prone to transient positivity (infections, other conditions) and is generally considered less specific than IgG, so persistence and correlation with clinical events matter. Confirm on repeat testing at least 12 weeks apart and interpret against the laboratory's own cutoff. The bodybuilder range equals the standard range.
When high
When positive/elevated (above the assay cutoff):
- A positive anticardiolipin IgM contributes to an antiphospholipid syndrome diagnosis but is less specific than IgG and is more often transient.
- What to do:
- Repeat testing at least 12 weeks later; isolated low-level IgM positivity may not be clinically significant.
- Interpret in the context of anti-B2 glycoprotein I, lupus anticoagulant, and any clinical clotting or pregnancy-loss history.
- Seek specialist review if positivity is persistent or accompanied by thrombosis; for AAS users, keep haematocrit controlled and discuss overall clot risk with a clinician.
History Chart
Reading History
Frequently Asked Questions
Reference Ranges
Standard Range
VitalMetrics Range