Sperm Aggregation
Fertility marker
Aggregation
Sperm Aggregation
Category: Fertility
Unit: grade
Sperm clumping to mucus, debris or non-motile cells, rather than to each other. Less specific than agglutination.
PED Notes
Usually non-specific and much less concerning than agglutination, but persistent aggregation alongside raised white cells can point to genital tract inflammation or infection, which is itself a driver of DNA fragmentation. Read it with the rest of the sample rather than on its own.
When high
Non-specific in isolation. It matters when it appears alongside other findings.
- With raised leukocytes: suggests genital tract inflammation or infection. Worth a semen culture and a clinician's opinion.
- With agglutination: see Agglutination, which is the more specific finding.
- On its own, with everything else normal: generally not acted on.
Infection and inflammation raise oxidative stress, so if this persists check Sperm DNA Fragmentation.
History Chart
Reading History
Frequently Asked Questions
Reference Ranges
Standard Range
Not available