Mesterolone (Proviron)

DHT derivative oral AAS. Weak anabolic, strong androgen. Used as an anti-estrogen adjunct and SHBG reducer to increase free testosterone.

Overview

AASDHT Derivative

DHT derivative oral AAS. Weak anabolic, strong androgen. Used as an anti-estrogen adjunct and SHBG reducer to increase free testosterone.

Effects on Markers

Dramatically lowers SHBG (increases free testosterone), mild anti-estrogenic effect, does not significantly suppress HPTA at low doses, minimal liver stress (not C17-alpha alkylated in the traditional sense), can worsen lipids moderately, may increase DHT-related sides (hair loss, prostate)

Compound Guide

Structure: 1-methyl DHT. Oral bioavailability via 1-methylation rather than 17-alpha alkylation, making it one of the least hepatotoxic oral AAS.

Dosage:

  • SHBG reduction / feel-good: 25-50mg/day
  • Anti-estrogen adjunct: 50mg/day alongside aromatising compounds
  • Enhancement: 50-75mg/day (limited anabolic effect — used for its androgenic and SHBG-lowering properties)

Administration:

  • Oral tablet, split into 2 doses/day (morning and evening)
  • Can be run for extended periods (8-12+ weeks) due to mild liver profile

Key Notes:

  • Primary value is dramatically lowering SHBG — more free testosterone from your existing testosterone base
  • Provides a "hardening" effect and improved mood/libido via increased free androgens
  • Very weak anabolic — do not expect significant muscle gains from Proviron alone
  • One of the few orals that can be run long-term without major liver concern
  • Can accelerate male pattern baldness in predisposed individuals (DHT derivative)
  • Useful during PCT to maintain androgenic activity and libido while HPTA recovers
  • Monitor lipids — can lower HDL moderately

Usage History

Frequently Asked Questions

Quick Reference

Category

AAS

Half-Life

12-13 hours

Detection Time

5-6 weeks

Usage Summary