Fertility DNA Test: What Your DNA Can, and Cannot, Tell You
Upload the raw DNA file you already have from 23andMe, AncestryDNA, MyHeritage, or FamilyTreeDNA, and get an honest, evidence-first read on fertility-relevant genetics. No marketing, no fear, no selling you a panic. Just what the science actually supports.
Runs entirely in your browser. Your DNA file never leaves your device.
What a fertility DNA analysis can actually check
Consumer DNA arrays genotype a fixed set of common variants. A few of them are genuinely fertility-relevant. We grade each one by the real evidence and the position of professional bodies like ACOG, ASRM, and ESHRE, rather than by what ranks or sells.
CFTR carrier status (male factor)
Evidence: strongCFTR variants cause congenital absence of the vas deferens, which accounts for up to 25% of obstructive azoospermia. Common CFTR variants are carried on consumer arrays, so carrier status is one of the few fertility findings a DNA file can legitimately surface.
Thrombophilia: Factor V Leiden, Prothrombin G20210A
Evidence: weak, informationalThese inherited clotting variants are often blamed for recurrent miscarriage, but ACOG, ASRM, and ESHRE advise against routine thrombophilia screening in fertility care because treatment benefit is unproven. We report them as context for a conversation with your clinician, not as a fertility diagnosis.
MTHFR C677T (the myth-buster)
Evidence: disprovenMTHFR is the single most over-hyped variant in fertility marketing. ACMG and CMS conclude it has no clinical utility in any scenario. We include it specifically to give you an honest answer, so no other site can sell you a supplement stack off a result that does not mean what they claim.
What your DNA file cannot tell you about fertility
This is the part most DNA tools quietly skip. A consumer SNP file is the wrong technology for the highest-yield genetic causes of infertility. If you are investigating real fertility problems, these need dedicated clinical tests, not a 23andMe upload.
Y-chromosome microdeletions
The leading genetic cause of low or absent sperm production. Needs targeted PCR testing, not a SNP array.
Karyotype and balanced translocations
A major cause of failed implantation and recurrent miscarriage. Arrays cannot see balanced rearrangements because no DNA is gained or lost.
Fragile X (FMR1) premutation
Linked to diminished ovarian reserve. It is a CGG repeat count that consumer chips do not measure.
Embryo aneuploidy (PGT-A)
The single biggest reason IVF cycles fail. It is tested on the embryos themselves, and is driven mostly by egg age, not your SNP profile.
Sperm DNA fragmentation
A functional sperm test, not a genetic variant. Your DNA file says nothing about it.
How it works
Use your existing file
Export your raw data from 23andMe, AncestryDNA, MyHeritage, or FamilyTreeDNA. No new test to buy.
Analyzed in your browser
Your file is read locally and never uploaded. We match it against a curated, referenced set of variants.
Get an honest report
Fertility findings sit alongside our compound, nutrition, and health-risk genetics, each graded by real evidence.
Fertility DNA questions, answered honestly
Can a DNA test tell me why I can't conceive?
Sometimes a piece of it, but usually not the whole answer. A consumer DNA file can flag a few fertility-relevant variants, like CFTR carrier status, which is genuinely linked to male-factor infertility. But the highest-yield genetic causes of infertility, such as Y-chromosome microdeletions, balanced chromosome translocations, and Fragile X, are not detectable from a 23andMe-style file at all. They need specific clinical tests ordered by a fertility specialist.
Does MTHFR cause infertility or miscarriage?
No, despite how often it is sold that way. The ACMG, CMS, and major reviews conclude MTHFR genotyping has no clinical utility in any scenario, including recurrent pregnancy loss. The MTHFR C677T variant is extremely common and is not a recognised cause of infertility, miscarriage, or clotting on its own. We include it in the analysis only to give you an honest, evidence-based answer instead of a panic.
Is Factor V Leiden a fertility problem?
Factor V Leiden and prothrombin G20210A are inherited clotting variants that have been studied in recurrent pregnancy loss, but ACOG, ASRM, and ESHRE all advise against routine thrombophilia screening in fertility evaluation, because it is unclear whether treatment improves outcomes. They matter more for general clotting risk around pregnancy, surgery, and oestrogen use. We report them as informational context, not as a fertility diagnosis.
Can 23andMe or AncestryDNA detect male infertility?
Only partially. These arrays can carry common CFTR variants, which are relevant to obstructive male infertility, so carrier status can show up. But they cannot detect Y-chromosome microdeletions, the most important genetic cause of low or absent sperm production, because that requires targeted PCR testing, not a SNP array. A semen analysis and a specialist workup remain essential.
Is my DNA data private?
Yes. The analysis runs entirely in your browser. Your raw DNA file is never uploaded to a server or stored by us. Nothing leaves your device.
Run your fertility DNA analysis
Free, private, and evidence-first. See your fertility-relevant variants alongside the full VitalMetrics genetic report, then take an informed list to your fertility specialist.
Analyze your DNAThis analysis is for informational and educational purposes only. It is not a diagnostic test, does not constitute medical advice, and cannot diagnose infertility or its causes. Consumer DNA data has real limits in accuracy and coverage, and any finding should be confirmed with clinical-grade testing. Always consult a qualified fertility specialist or genetic counsellor about your individual situation.