Melanotan II
Synthetic melanocortin receptor agonist. Used for skin tanning, libido enhancement, and appetite suppression. Also improves erectile function.
Overview
Synthetic melanocortin receptor agonist. Used for skin tanning, libido enhancement, and appetite suppression. Also improves erectile function.
Effects on Markers
No significant impact on standard blood markers. Does not affect hormones, lipids, or haematology. Can cause nausea, facial flushing, and increased mole pigmentation. Primarily acts on melanocortin receptors in skin and brain.
Compound Guide
Structure: Synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (alpha-MSH). Binds MC1R (tanning), MC3R/MC4R (libido, appetite).
Dosage:
- Loading phase: 250-500mcg/day SubQ for 2-3 weeks (until desired tan develops)
- Maintenance: 250-500mcg 1-2x/week to maintain tan
- Libido effect: occurs at loading doses, less consistent at maintenance
Administration:
- SubQ injection, abdomen, preferably before UV exposure (tanning beds or sun)
- 27-30g insulin syringe
- Start low (100-250mcg) to assess nausea tolerance
Key Notes:
- UV exposure is still required — Melanotan II accelerates and deepens the tanning response, it does not tan without UV
- Nausea is very common at initial doses — typically subsides after a few days
- Facial flushing occurs 1-4 hours post-injection — normal and temporary
- Can darken existing moles and freckles — monitor any changes in mole appearance
- Libido and erectile function enhancement is a notable side effect
- Appetite suppression can be significant — useful during cutting phases
- No impact on standard bloodwork panels
- Reconstitute with bacteriostatic water, store refrigerated and away from light (photosensitive)
Usage History
Frequently Asked Questions
Quick Reference
Category
Peptide
Half-Life
~1 hour
Detection Time
N/A