HMG
Human Menopausal Gonadotropin. Contains both FSH and LH activity. Used for fertility restoration post-AAS, more effective than HCG alone for spermatogenesis.
Overview
Human Menopausal Gonadotropin. Contains both FSH and LH activity. Used for fertility restoration post-AAS, more effective than HCG alone for spermatogenesis.
Effects on Markers
Directly stimulates FSH and LH receptors, promotes spermatogenesis (FSH component) and testosterone production (LH component), more effective than HCG alone for fertility recovery, can elevate estradiol
Compound Guide
Structure: Urinary-derived gonadotropin containing both FSH and LH in roughly equal proportions. Provides direct gonadotropin stimulation.
Dosage:
- Fertility restoration: 75-150 IU every other day for 3-6 months
- Combined with HCG: HCG 1000-1500 IU 2x/week + HMG 75 IU 3x/week
- Aggressive protocol: HMG 150 IU EOD + HCG 1500 IU 2x/week
Administration:
- IM or SubQ injection
- Reconstitute with provided diluent or bacteriostatic water
- Cycle length for fertility: 3-6 months minimum (spermatogenesis takes ~74 days per cycle)
Key Notes:
- The FSH component is critical for spermatogenesis — HCG alone only provides LH activity
- Gold standard for post-AAS fertility restoration when HCG alone is insufficient
- Expensive — often reserved for when fertility is the primary goal
- Semen analysis should be performed at baseline and every 2-3 months during treatment
- Can elevate estradiol — monitor E2 and manage if symptomatic
- Monitor: LH, FSH, testosterone, E2, semen analysis (count, motility, morphology)
- Full fertility recovery can take 6-12+ months after prolonged AAS use
Usage History
Markers to Monitor
Frequently Asked Questions
Quick Reference
Category
Peptide
Half-Life
~24 hours
Detection Time
N/A