Arachidonic Acid to EPA Ratio (AA/EPA)
Lipids marker
Arachidonic Acid/EPA Ratio
Arachidonic Acid to EPA Ratio (AA/EPA)
The ratio of arachidonic acid (omega-6) to EPA (omega-3) in the fatty-acid profile. It summarises the balance between pro-inflammatory and anti-inflammatory eicosanoid precursors, with a lower ratio reflecting a more favourable, less inflammatory balance.
PED Notes
The AA/EPA ratio is arguably the most practically useful single number on an omega fatty-acid panel, because it captures the inflammatory balance in one figure. A high ratio (lots of arachidonic acid, little EPA) indicates a pro-inflammatory state; a lower ratio indicates that omega-3 intake is adequate to offset omega-6. It responds quickly and predictably to fish-oil supplementation, dropping as EPA rises, which makes it a good way to confirm an omega-3 protocol is working. For AAS users this is a cheap, modifiable lever that supports cardiovascular and general inflammatory health without any downside to the physique. Lower is generally better; values are matrix and method dependent.
When high
When the AA/EPA ratio is high (pro-inflammatory balance):
- Raise EPA to bring the ratio down; this is more effective and sensible than trying to lower arachidonic acid.
- Fish oil (EPA/DHA) -- 2-3g combined per day with food; higher-EPA formulas move the ratio fastest
- Oily fish -- 2-3 servings/week
- Reduce excess omega-6 from industrial seed oils and processed foods
- Recheck after 8-12 weeks; the ratio typically improves noticeably with consistent EPA intake
History Chart
Reading History
Frequently Asked Questions
Reference Ranges
Standard Range
VitalMetrics Range