Bioavailable Testosterone

Hormones marker

Bioavailable Testosterone

Category: Hormones
Unit: nmol/L

Testosterone that is free or loosely bound to albumin. Represents the portion available to tissues (free T + albumin-bound T).

PED Notes

Bioavailable testosterone includes both free testosterone and albumin-bound testosterone (which can readily dissociate). It excludes only SHBG-bound testosterone. This is a more comprehensive measure of 'usable' testosterone than free T alone. Common on US lab panels (Quest, LabCorp) where it's reported in ng/dL. On AAS/TRT, bioavailable T will be elevated proportionally to total T, modified by SHBG status.

Understanding Bioavailable T:

  • Bioavailable T = Free T + Albumin-bound T (approximately 30-50% of total T)
  • SHBG-bound T is NOT bioavailable (tightly bound, does not dissociate at tissues)
  • More clinically useful than total T when SHBG is abnormal

If low (off-cycle):

  • Check total T, free T, and SHBG to understand the cause
  • High SHBG will lower bioavailable T even with normal total T
  • See Free Testosterone and SHBG management protocols

If elevated (on cycle/TRT):

  • Expected -- no intervention needed unless experiencing side effects
  • Monitor androgenic side effects (acne, hair loss, prostate symptoms)

Supplements & Lifestyle:

  • Same protocols as Free Testosterone
  • Boron (10mg/day) can lower SHBG and increase bioavailable fraction

References:

  • Naghii, M. R., Mofid, M., Asgari, A. R., Hedayati, M., & Daneshpour, M.-S. (2011). Comparative effects of daily and weekly boron supplementation on plasma steroid hormones. Journal of Trace Elements in Medicine and Biology, 25(1), 54-58. DOI: 10.1016/j.jtemb.2010.10.001
  • Pilz, S., Frisch, S., Koertke, H., et al. (2011). Effect of vitamin D supplementation on testosterone levels in men. Hormone and Metabolic Research, 43(3), 223-225. DOI: 10.1055/s-0030-1269854

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Reference Ranges

Standard Range

3.8 - 20 nmol/L

VitalMetrics Range

7 - 24 nmol/L

Statistics