Mean Platelet Volume
Haematology marker
MPV
Mean Platelet Volume
Category: Haematology
Unit: fL
Average size of platelets. Larger platelets are younger and more reactive. Can indicate bone marrow activity.
PED Notes
Not directly affected by AAS. May increase when platelet turnover is high (e.g. from heavy training-induced microtrauma). Persistently elevated MPV with low platelets warrants investigation.
When high
When elevated (>13.0 fL -- large, young platelets):
- Indicates increased platelet turnover -- bone marrow producing larger, more reactive platelets to compensate for destruction or consumption
- High MPV + low platelet count = platelets being consumed/destroyed faster than produced (investigate immune thrombocytopenia, chronic inflammation)
- High MPV + normal platelet count = usually benign, may reflect recent intense training
- Elevated MPV is an independent cardiovascular risk marker in some studies (larger platelets are more thrombogenic)
Note: MPV is most useful when interpreted alongside platelet count rather than in isolation. No specific supplements directly target MPV.
When low
When low (<7.0 fL -- small, old platelets):
- May indicate bone marrow underproduction (aplastic conditions) or certain inflammatory states
- Low MPV + low platelets = possible bone marrow issue -- warrants haematology referral
- Low MPV + normal platelets = usually not clinically significant
Note: MPV is most useful when interpreted alongside platelet count rather than in isolation. No specific supplements directly target MPV.
History Chart
Reading History
Frequently Asked Questions
Reference Ranges
Standard Range
7 - 13 fL