Mean Corpuscular Haemoglobin
Haematology marker
MCH
Mean Corpuscular Haemoglobin
Category: Haematology
Unit: pg
Average amount of haemoglobin per red blood cell.
PED Notes
Not typically affected by AAS. Low MCH with low MCV suggests iron deficiency, common in athletes who donate blood regularly to manage high haematocrit.
When low (<27 pg -- parallels low MCV):
Cause: Almost always iron deficiency. In AAS users, typically from regular blood donation depleting iron stores while erythropoiesis remains stimulated.
Supplements:
- Iron Bisglycinate -- 25-50mg/day with Vitamin C 500mg for absorption
- Vitamin C -- 500mg taken with iron to enhance absorption
Follow-up:
- Confirm with iron studies (Ferritin, Serum Iron, Transferrin Saturation)
- MCH normalises alongside MCV as iron stores replenish (8-12 weeks)
- If MCH is low but iron studies are normal, investigate thalassaemia trait
When high (>33 pg):
- Usually parallels high MCV (macrocytosis) -- check B12 and Folate
- Rarely clinically significant in isolation
References:
- Camaschella, C. (2015). Iron-deficiency anemia. New England Journal of Medicine, 372(19), 1832-1843. DOI: 10.1056/NEJMra1401038
- Stabler, S. P. (2013). Vitamin B12 deficiency. New England Journal of Medicine, 368(2), 149-160. DOI: 10.1056/NEJMcp1113996
History Chart
Reading History
Frequently Asked Questions
Reference Ranges
Standard Range
27 - 33 pg