Glycated Haemoglobin (IFCC)
Glucose Metabolism marker
HbA1c (IFCC)
Glycated Haemoglobin (IFCC)
IFCC-standardised HbA1c measurement. Same marker as HbA1c % but in SI units. Normal: <42 mmol/mol. Pre-diabetes: 42-47. Diabetes: >=48. Conversion: mmol/mol = (% - 2.15) x 10.929.
PED Notes
Equivalent to HbA1c % — same clinical significance. GH use can worsen HbA1c over time, indicating insulin resistance. High haematocrit from AAS can affect accuracy of some HbA1c assays. Australian labs report both units; mmol/mol is the IFCC standard.
When high
Same marker as HbA1c % -- identical management applies (see HbA1c marker).
IFCC units (mmol/mol) are simply a different scale. Targets: <37 mmol/mol optimal for athletes (<5.5%). Conversion: mmol/mol = (% - 2.15) x 10.929.
Supplements:
- Berberine -- 500mg 2-3x/day
- Alpha-Lipoic Acid (ALA) -- 300-600mg/day
Lifestyle:
- Low-glycaemic diet, regular cardio and strength training
- If HbA1c trending upward on GH, consider dose reduction
Pharmacological options (when supplements are insufficient):
- Metformin -- 500-2000mg/day; first-line; also has longevity/mTOR evidence
- Semaglutide / Tirzepatide -- 0.25-2.4mg or 2.5-15mg subQ weekly; GLP-1 (or GLP-1/GIP) agonist; reduces HbA1c 1-2 percentage points
- Acarbose -- 25-100mg with main carb meals; alpha-glucosidase inhibitor
- Empagliflozin / Dapagliflozin (SGLT2 inhibitors) -- 10-25mg/day; cardiovascular and renal protective
- Pioglitazone -- 15-30mg/day; PPAR-gamma insulin sensitiser; reserved for severe IR
- Reduce or pause exogenous GH -- GH antagonises insulin; dose reduction is often the most effective single intervention
- All require physician oversight
History Chart
Reading History
Frequently Asked Questions
Reference Ranges
Standard Range
VitalMetrics Range