Calcium

Electrolytes marker

Calcium

Category: Electrolytes
Unit: mmol/L

Essential mineral for bones, muscles, and nerve function.

PED Notes

Generally stable on AAS. Adequate vitamin D and calcium intake important for bone health and muscle function.

When low (hypocalcemia):

Supplements:

  • Calcium Citrate -- 500-1000mg/day (split doses, better absorbed than carbonate; take with meals)
  • Vitamin D3 -- 5000 IU/day (essential for calcium absorption; deficiency is the most common cause of low calcium in athletes)
  • Vitamin K2 (MK-7) -- 100-200mcg/day (directs calcium to bones, prevents arterial calcification)
  • Magnesium -- 400mg/day (required for calcium metabolism and PTH function)

Lifestyle:

  • Increase dietary calcium: dairy, fortified plant milks, sardines, leafy greens
  • Check Vitamin D levels -- correct deficiency first as it drives calcium absorption
  • If on AI (Anastrozole/Exemestane), low estradiol can impair calcium homeostasis long-term

When high (hypercalcemia):

  • Rare in athletes -- investigate parathyroid function (PTH), excessive Vitamin D supplementation, or malignancy
  • Reduce Vitamin D and calcium supplementation if over-supplementing
  • Increase fluid intake to promote renal calcium excretion
  • Persistent hypercalcemia warrants endocrinology referral

References:

  • Yao, P., Bennett, D., Mafham, M., et al. (2019). Vitamin D and calcium for the prevention of fracture. JAMA Network Open, 2(12), e1917789. DOI: 10.1001/jamanetworkopen.2019.17789
  • Holick, M. F. (2007). Vitamin D deficiency. New England Journal of Medicine, 357(3), 266-281. DOI: 10.1056/NEJMra070553
  • Institute of Medicine. (2011). Dietary reference intakes for calcium and vitamin D. National Academies Press. DOI: 10.17226/13050

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Frequently Asked Questions

Reference Ranges

Standard Range

2.1 - 2.6 mmol/L

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